Formulasi Sediaan Nano Herbal Tempuyung (Sonchus arvensis L.) dalam Bentuk Self Nano-Emulsifying Drug Delivery System (SNEDDS)
نویسندگان
چکیده
منابع مشابه
Self Nano Emulsifying Drug Delivery Systems for Oral Delivery of Hydrophobic Drugs
Self-emulsifying drug delivery systems (SNEDDS) are highly in quest due to their innumerable benefits like better portability, improved stability and higher drug loading, coupled with ease and economy of their production. SNEDDS are used to improve the solubility of high lipophilic drugs. SNEDDS are improving the oral bioavailability of limited water-soluble drug compounds. These SNEDDS are iso...
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Purpose: To prepare and characterize tablets loaded with self-nanoemulsifying drug delivery system (SNEDDS) containing docetaxel (DTL). Method: SNEDDS of docetaxel were prepared using various oils, surfactants, co-surfactant and solvents to improve the dissolution rate and bioavailability of the poorly water-soluble chemotherapeutic agent. The SNEDDS components were preliminarily screened for t...
متن کاملDrug Delivery System in Nano Greens
Herbal medicines have been widely used all over the world since ancient times and have been recognized by physicians and patients for their better therapeutic value as they have fewer adverse effects as compared with modern medicines. Herbal therapeutics can be achieved by Drug Delivery systems. This herbal treatment helps to increase the therapeutic value by reduce the toxicity and side effect...
متن کاملEvaluation of Teratogenic Effect of Tempuyung (Sonchus arvensis) Extract on Wistar Rats
Objectives: this study was conducted to obtain safety data of ethanolic extract of tempuyung leaves (EETL) on pregnant Wistar rats. Methods: Four groups of rats were used for this study, including control group, ethanolic extract of tempuyung leaves (EETL) at doses of 100 mg.kg, 400 mg.kg and 1000 mg.kg, in which each group consisted of ten pregnant rats. Extracts were administered once daily s...
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Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. From time to time many workers have claimed various rational applications of Self-emulsifying formulation...
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ژورنال
عنوان ژورنال: Jurnal Sains Farmasi & Klinis
سال: 2016
ISSN: 2442-5435,2407-7062
DOI: 10.29208/jsfk.2016.3.1.99